Charles University, Faculty of Medicine in Pilsen

Charles University (Universitas Carolina) was founded by  Roman Emperor and King of Bohemia Charles the Fourth in 1348. Faculty of Medicine in Pilsen (CU-FMP) is one of the 17 faculties of Charles University  settled in the west-bohemian city of Pilsen. Except of education in General Medicine and Dentistry, CU-FMP is active in biomedical research in the fields of the replacement of function of vital organs like liver, kidney and homeostasis, including clinical experimental work on large animal models and modeling of the sepsis nad  organism response on systemic infections. The experimental research takes place in Biomedical Center. The Department of the Imaging, the united department of Medical Faculty and University Hospital in Pilsen is active in the experimental research in Biomedical Center of the advanced  imaging techniques including the imaging of animal experiments using computed tomography.  

The Imaging research program contains the development of new imaging techniques using  computed tomography, the latest  program  started since 2020 is involved in the development of the photon-counting CT. The world-wide first human scans of the ill patients with photon-counting CT using clinical-prototype were performed in Pilsen during 2020 in collaboration with Siemens-Healthineers CT development and research group. The collaboration resulted in the first publication of clinical results with photon-counting CTin humans. Contemporary, the current research  continues in the development of new imaging  ways using dual-source photon-countin CT. The photon-counting CT program  followed the  previous research on the field of the cardiovascular imaging  and  dual-energy imaging of tissues including brain, lungs and kidneys, and the perfusion imaging of the myocardium. 

Except the imaging using computed tomography, the second flagship of the research is the molecular imaging using  hybrid imaging with PET/CT and PET/MRI with advanced radoopharmaceuticals or imaging concepts, the most important are imaging of the inflammation in  immunocompromised patients, the advanced imaging of malignant tissues targeting proliferation,  microenvironment and tissue hypoxia. The Department of the Imaging of Medical Faculty and University Hospital in Pilsen is equipped by 6 computed tomography  suites, 3 suites of magnetic resonances,  3 suites of hybrid imaging (PET/CT, PET/MRI, SPECT/CT), and two cath-labs, the staff of 190 people includes 60 medical doctors.

Role in the project

Charles University, Faculty of Medicine in Pilsen, Department of the Imaging, provides imaging and clinical data and contributes imaging experience in  cardiovascular imaging with advanced applications of photon-counting CT to the AI-POD project.


Jiří Ferda
Prof. Jiří Ferda, M.D., Ph.D., professor of Radiology, head of Department of the Imaging, and  head of Institute of Anatomy, vice-dean for education, his practice contains  29 years of the experience with CT imaging, he is born-certified in Radiology, Neuroradiology, Vascular Interventional Radiology and Nuclear Medicine.  His  research activities include the  dual energy CT  and photon-counting CT  imaging, and the imaging using advanced applications of  PET/CT and PET/MRI.

The key publications are Ferda J, Vendiš T, Flohr T et al. Computed tomography with a full FOV photon-counting detector in a clinical setting, the first experience. Eur J Radiol. 2021; Ferda J, Ferdová E, Hes O,  et. al.  PET/MRI: Multiparametric imaging of brain tumors. Eur J Radiol. 2017; Ferda J, Hromádka M, Baxa J. Imaging of the myocardium using (18)F-FDG-PET/MRI. Eur J Radiol. 2016; Ferda J, Ferdová E, Záhlava J, Matejovic M, Kreuzberg B. Fever of unknown origin: a value of (18)F-FDG-PET/CT with integrated full diagnostic isotropic CT imaging. Eur J Radiol. 2010; Ferda J, Novák M, Mírka H et al.. The assessment of intracranial bleeding with virtual unenhanced imaging by means of dual-energy CT angiography. Eur Radiol. 2009

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